diff --git a/apps/runner/supervisor.mjs b/apps/runner/supervisor.mjs
index 6586355..e178e75 100644
--- a/apps/runner/supervisor.mjs
+++ b/apps/runner/supervisor.mjs
@@ -246,6 +246,41 @@ const server = createServer(async (req, res) => {
         const pkg = { name: `mcp-${name}`, private: true, dependencies: { [npxPackage]: "*" } };
         writeFileSync(join(svcSourcePath, "package.json"), JSON.stringify(pkg, null, 2));
         svcRuntime = svcRuntime || "node";
+      } else if (body.uvxPackage) {
+        // uvx-based Python MCP: install via uv and find the entry point
+        svcSourcePath = join("/var/claudemesh/services", name);
+        mkdirSync(svcSourcePath, { recursive: true });
+        const { execSync } = await import("node:child_process");
+        try {
+          execSync(`uv venv ${join(svcSourcePath, ".venv")}`, { timeout: 30_000, stdio: "pipe" });
+          execSync(`${join(svcSourcePath, ".venv/bin/pip")} install ${body.uvxPackage}`, { timeout: 120_000, stdio: "pipe" });
+          console.log(`[runner] uvx package installed: ${body.uvxPackage}`);
+        } catch (e) {
+          return json(res, 500, { error: `uvx install failed: ${e.message}` });
+        }
+        // Find the MCP binary in the venv
+        const venvBin = join(svcSourcePath, ".venv/bin");
+        if (existsSync(venvBin)) {
+          const bins = readdirSync(venvBin).filter(b => !["python", "python3", "pip", "pip3", "activate", "Activate.ps1", "activate.csh", "activate.fish", "deactivate"].includes(b) && !b.startsWith("python3."));
+          const pkgShort = body.uvxPackage.split("/").pop().replace(/^@/, "");
+          const match = bins.find(b => b.includes(pkgShort.replace(/-/g, ""))) || bins.find(b => b.includes("mcp")) || bins[0];
+          if (match) svc._npxBin = join(venvBin, match);
+        }
+        svcRuntime = "python";
+        // Skip normal installDeps — already installed via uv
+        const svc2 = { name, sourcePath: svcSourcePath, runtime: svcRuntime, env: svcEnv || {}, process: null, pid: null, tools: [], status: "running", pending: new Map(), logs: [], restarts: 0, healthFailures: 0, _npxBin: svc?._npxBin };
+        Object.assign(svc, svc2);
+        services.set(name, svc);
+        spawnService(svc);
+        await new Promise(r => setTimeout(r, 1500));
+        try {
+          svc.tools = await initMcp(svc);
+          console.log(`[runner] ${name} ready (uvx), ${svc.tools.length} tools`);
+          return json(res, 200, { status: "running", tools: svc.tools });
+        } catch (e) {
+          svc.status = "failed"; svc.logs.push(`MCP init failed: ${e.message}`);
+          return json(res, 500, { error: e.message, logs: svc.logs.slice(-10) });
+        }
       } else if (!svcSourcePath) {
         return json(res, 400, { error: "one of sourcePath, gitUrl, or npxPackage required" });
       }